Methanol, 1-(triethylsilyl)-
(triethylsilyl)methanol
CAS: 60764-82-1
Molecular Formula: C7H18OSi
Methanol, 1-(triethylsilyl)- - Names and Identifiers
| Name | (triethylsilyl)methanol |
| Synonyms | Triethylsilylmethanol (triethylsilyl)methanol Methanol, 1-(triethylsilyl)- |
| CAS | 60764-82-1 |
| InChI | InChI=1/C7H18OSi/c1-4-9(5-2,6-3)7-8/h8H,4-7H2,1-3H3 |
Methanol, 1-(triethylsilyl)- - Physico-chemical Properties
| Molecular Formula | C7H18OSi |
| Molar Mass | 146.3 |
| Density | 0.8557 g/cm3 |
| Boling Point | 80-81 °C(Press: 20 Torr) |
| Flash Point | 71.6°C |
| Vapor Presure | 0.144mmHg at 25°C |
| pKa | 15.50±0.10(Predicted) |
| Refractive Index | 1.418 |
Methanol, 1-(triethylsilyl)- - Introduction
(triethylsilyl)methanol is an organosilicon compound with the chemical formula (C2H5)3 SiCH2OH. The following is a description of some of the properties, uses, methods and safety information about (triethylsilyl)methanol:
Nature:
-Appearance:(triethylsilyl)methanol is generally colorless or light yellow liquid.
-Solubility: It is soluble in common organic solvents, such as ethanol, ether and chloroform.
-Stability:(triethylsilyl) The methanol is stable at room temperature, but may react when encountering strong oxidants.
Use:
-Reagent:(triethylsilyl)methanol is commonly used as a reagent in organic synthesis reactions, for example, as a protective group introduction agent and alcohol protective agent.
-Catalyst: It can also be used as a catalyst for organic synthesis reactions, such as the esterification of carboxylic acids.
-Intermediate:(triethylsilyl)methanol can also be used to synthesize other organosilicon compounds, such as organosilanes and organosilicon ethers.
Preparation Method:
(triethylsilyl)methanol common preparation methods are as follows:
-Cyclization by silanol: Silanol is reacted with methanol under acidic conditions, and (triethylsilyl)methanol is obtained through dehydration cyclization reaction.
-Reverse silicone alcoholation: (triethylsilyl)methanol is obtained by reacting triethyl silicone with methanol under acidic conditions.
Safety Information:
- (triethylsilyl)methanol is a flammable liquid, need to be stored in a cool, ventilated place.
-use should avoid contact with skin and eyes, such as contact should immediately rinse with plenty of water, and seek medical help.
-Pay attention to fire prevention measures during operation and storage to avoid static electricity accumulation.
-Waste disposal should follow local and national environmental regulations to avoid environmental pollution.
Nature:
-Appearance:(triethylsilyl)methanol is generally colorless or light yellow liquid.
-Solubility: It is soluble in common organic solvents, such as ethanol, ether and chloroform.
-Stability:(triethylsilyl) The methanol is stable at room temperature, but may react when encountering strong oxidants.
Use:
-Reagent:(triethylsilyl)methanol is commonly used as a reagent in organic synthesis reactions, for example, as a protective group introduction agent and alcohol protective agent.
-Catalyst: It can also be used as a catalyst for organic synthesis reactions, such as the esterification of carboxylic acids.
-Intermediate:(triethylsilyl)methanol can also be used to synthesize other organosilicon compounds, such as organosilanes and organosilicon ethers.
Preparation Method:
(triethylsilyl)methanol common preparation methods are as follows:
-Cyclization by silanol: Silanol is reacted with methanol under acidic conditions, and (triethylsilyl)methanol is obtained through dehydration cyclization reaction.
-Reverse silicone alcoholation: (triethylsilyl)methanol is obtained by reacting triethyl silicone with methanol under acidic conditions.
Safety Information:
- (triethylsilyl)methanol is a flammable liquid, need to be stored in a cool, ventilated place.
-use should avoid contact with skin and eyes, such as contact should immediately rinse with plenty of water, and seek medical help.
-Pay attention to fire prevention measures during operation and storage to avoid static electricity accumulation.
-Waste disposal should follow local and national environmental regulations to avoid environmental pollution.
Last Update：2024-04-10 22:29:15
